Available [Q1] 2027

Designed to Secure.
Engineered to Protect.

Cannusafe™ is the first universal cannula securement device for intraocular surgery — protecting every syringe-cannula junction, in every procedure, with a single one-second application.

84%
of surgeons have experienced cannula detachment

24M
intraocular procedures per year worldwide

$204M
global health economy cost annually

Amar Alwitry - The Inventor

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CE Certified at lanuch EU MDR Compliant FDA Class 1 Exempt Patent WO2025/163287A1

THE DEVICE

Two Mandatory Requirements.
One Elegant Solution.

Cannusafe™ is a precision-cut medical tape with a central aperture and two adhesive arms. Applied by the scrub practitioner in approximately one second during syringe preparation. The surgeon is entirely uninvolved. No training required. No workflow impact.

The Science

PATIENT SAFETY

Mechanical Cannula Security

The cannula tip threads through the central aperture. Even if the Luer lock fully disengages under injection pressure, the cannula physically cannot pass through the aperture and cannot enter the eye. Compatible with 1 ml, 2 ml, 3 ml and 5 ml syringes — every junction in every procedure is protected.

Two Royal College of Ophthalmologists safety alerts
84% of surgeons have experienced detachment
Published medicolegal duty of care established

REGULATORY COMPLIANCE

Integrated Mandatory Labelling

Cannusafe incorporates a clearly visible labelling surface enabling mandatory syringe identification compliance. No separate adhesive labels required. Compliance is automatic — a consequence of device application, not an additional step.

Joint Commission NPSG.03.04.01 (USA)
BS ISO 26825:2020 / EN ISO 26825:2022 (Europe)
ACSQHC National Labelling Standard (Australia)

With such a simple, cheap and effective safety solution available, it should be used for all intraocular procedures and failure to do so would be deemed to be a breach of the duty of care to the patient.

Eye (Lond). 2026 Mar 24 — Peer-reviewed published analysis

FOR SURGEONS

The Problem You Know.
The Solution That Works.

Cannula detachment during intraocular surgery is a documented, recurring cause of avoidable harm. You know this. You may have experienced it. Two Royal College of Ophthalmologists safety alerts have formally identified it as a continued trend.

The Luer lock has failed to eliminate the risk. The screw cap solutions and clips some manufacturers utilise show that the problem is recognised but they protect one syringe only - leaving every other junction in the same procedure unprotected. Plastic based solutions would add massive amounts of plastic wastage as well as cost.

Applied by your scrub practitioner during pack preparation. You never touch it. Your workflow is unchanged. Your patients are protected.

View the Evidence

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Attach cannula to syringe as normal
No change to the standard preparation process
Thread cannula tip through central aperture
The aperture is sized to allow the cannula through but arrest the hub on any detachment
Peel adhesive arms and press to syringe barrel
Secure on both sides — the cannula is now mechanically protected
Label and hand to surgeon — done
The integrated labelling surface is ready to use. Total application time: approximately one second.

The visible cases are the tip of the iceberg.

Cannula detachment is dramatically under-reported. Published incident rates capture only those cases that resulted in formal litigation or regulatory notification. The reality on the operating theatre floor is very different: events are absorbed into the surgical record, attributed to other causes, or simply normalised as part of the unpredictability of surgery.

This is why surgeon-experience data tells the truer story. In a published survey of 551 ophthalmic surgeons, 84% had personally experienced cannula dislocation, 78% had seen the patient harmed as a result, and 50% reported ocular damage from the last episode they witnessed. These are not rare events. They are everyday risks that have been hidden in plain sight.

Waiting for the published incident data to “catch up” is not a safety strategy. The data that matters is already in front of us — in every surgeon’s direct experience.

Find out more about Under Reporting

FOR HEALTCARE SETTINGS

Your Duty of Care.
Our Solution.

Every hospital, surgical centre, and healthcare provider performing intraocular surgery — whether in the UK, the USA, Europe, or anywhere in the world — has a duty of care to ensure the equipment used is safe and fit for purpose. Once Cannusafe is commercially available, that duty is clear.

The published medicolegal analysis in Eye (Lond.) 2026 is unambiguous: failure to use an available safety device of this type constitutes a breach of the duty of care to the patient. Formal patient safety submissions have been made to the WHO, NHS England, NHS Resolution and the US FDA highlighting the case for adoption.

Cannusafe simultaneously addresses mandatory syringe labelling obligations under Joint Commission NPSG.03.04.01 (USA), BS ISO 26825:2020 (UK/Europe), and equivalent international standards, eliminating the need to purchase separate sterile label strips — a direct procurement cost saving in every market where Cannusafe is used.

The health economy case is compelling across all major markets. The figures below show the annual financial burden of cannula detachment and the estimated net savings from universal Cannusafe adoption:

Cannusafe Sustainability

UNITED KINGDOM

£6.56M

Annual UK health economy burden — care costs and clinical negligence claims

£5M+

Estimated annual net UK saving with universal Cannusafe adoption: £5M+

UNITED STATES

$57.95

Annual US health economy burden — $17.1M litigation costs and $40.8M additional PCR care costs

£40M+

Estimated annual net US saving with universal Cannusafe adoption: $40M+

GLOBAL

$204M

Published annual global health economy saving from universal adoption — peer-reviewed Eye (Lond.) 2026

$90M+

Estimated net global saving after Cannusafe cost: $90M+

2128

Episodes of avoidable ocular harm per year in the UK from this single preventable cause

1 sec

Application time. No surgical delay. No theatre time lost. Surgeon uninvolved.

APPROACH	CURRENT PRACTICE	With Cannusafe™
All syringe sizes protected	✗	✓
Mandatory labelling compliance	✗ Inconsistent	✓ Automatic
Surgeon workflow disruption	None	None
Training required	None	None
Duty of care discharged	✗	✓

FOR PHACO PACK PROVIDERS

The Only Safety Device
Your Pack Needs.

Cannusafe is supplied as a single sterile device in a sealed pouch — ready to be incorporated into your existing pack manufacturing process. The sealed pouch sits inside your pack and is sterilised together with the rest of the pack contents using your normal ethylene oxide (EtO) cycle. Double-sterilisation has been confirmed by the manufacturer; full material certification is supplied.

Adding Cannusafe to your pack simultaneously addresses two requirements your customers face: cannula safety and syringe labelling compliance.

Luer lock syringe and cannula attachments - standard in surgical consumable packs - carry a known and recurring safety risk. The published incident data substantially under-represents the true clinical reality of cannula detachment.

Several major manufacturers have already indicated a desire to incorporate Cannusafe into their packs.

Without inclusion, end users carry the cost and complexity. Where Cannusafe is not in the pack, end users must purchase it separately - adding procurement complexity and unit cost that pack-level inclusion would resolve.

Incorporate or recommend: Pack providers are well-placed to lead on this issue. Where direct incorporation isn't possible, including a recommendation to use a safety device - Cannusafe or another equivalent - in pack documentation protects patients, supports your customers, and strengthens your own patient-safety positioning.

Simple integration. Sealed pouch drops directly into your existing pack; sterilised with the rest of the pack on your EtO cycle.

Eliminates separate label component. Cannusafe’s integrated labelling surface replaces separate sterile syringe labels, offsetting cost and reducing BOM complexity.

Patient safety credentials. CE marked, EU MDR compliant, FDA Class I exempt, supported by peer-reviewed evidence and formal patient safety endorsements.

📦

Unsterilised Bulk Supply

EtO-compatible bulk format with full material certification. Integrates directly into your existing pack manufacturing and sterilisation process.

🏷️

Eliminates Separate Label Component

Cannusafe's integrated labelling surface replaces separate sterile syringe labels — reducing your pack BOM and procurement complexity simultaneously.

🛡️

Discharges Your Duty of Care

Published peer-reviewed analysis establishes that pack providers supplying procedures without Cannusafe — knowing a competitor has adopted it — face indefensible liability.

FOR PHACO PACK PROVIDERS

"With such a simple, cheap and effective safety solution available, it should be used for all intraocular procedures and failure to do so would, in my view, be deemed to be a breach of the duty of care to the patient."

Eye (Lond). March 2026

Peer-reviewed published analysis. Editor: Prof Harminder Dua, immediate past President, Royal College of Ophthalmologists.

"The Cannusafe™ sleeve is a simple, low-cost solution that can be easily integrated into current practices without disrupting standard procedures. Confirmation of its application should be mandated as part of the WHO safety checklist."

Tracy Coates RGN

Former National Patient Safety Lead, NPSA · Former President, Association for Perioperative Practice · Former Safety and Learning Lead, NHS Resolution

"Despite the use of Luer locks, 60 cases of cannula detachment were reported; 196 respondents experienced this complication, and the most common cause was stromal hydration (50%). Some serious complications were reported: retinal damage (9%) and vitreous loss (17%)."

Pandey & Kirkby. Canadian Journal of Ophthalmology. 2012

The problem has been documented for over a decade. For 13 years there was no solution. Cannusafe™ is the answer.

THE CALL TO INDUSTRY FOR A SOLUTION FROM INFLUENCIAL US BODY

An independent specification - that Cannusafe meets

Survey of 551 ophthalmic surgeons: 84% had experienced cannula dislocation; 78% had seen resulting harm; 50% reported ocular damage the last time it occurred; 87% felt a safety device was required.
Alwitry A. J Cataract Refract Surg. 2025;51(11):1034–1036

Estimated UK annual health economy burden: approximately £6.56 million per year in additional care costs and clinical negligence claims. Global burden: $204 million per year. US burden alone: $57.95 million per year.
Eye (Lond). 2026 · Lubeck et al. Expert Review of Ophthalmology. 2025

Stephen Rowley, Clinical Director, Association for Safe Aseptic Practice and originator of the ANTT® Clinical Practice Framework, has formally endorsed Cannusafe and highlighted limitations of the screw cap alternative including sharps risk and ANTT non-compliance.
ASAP Clinical Opinion. October 2025

PUBLISHED LITERATURE

The clinical problem has been recognised and documented in peer-reviewed literature for more than a decade. Numerous papers have reported the injuries, the frequency, and the consequences. Royal College of Ophthalmologists safety alerts have been issued. Until Cannusafe™, no adequate solution existed.

"Simple statements that Luer-locks never fail will not avoid future harm if human performance shortfalls cannot be eliminated from every possible step. The safest way to do this is at the manufacturing stage by moulding one-piece cannula-syringe devices — eliminating the possibility of detachment by force or inadequate tightening."

Wilde C, Ross AR, Orr G, Dua H. Eye (Lond). 2019;33:341–342

This approach — redesigning every syringe — is not financially feasible. It would require new tooling for every syringe size from every manufacturer. Cannusafe™ achieves the same protection in a single universal device, applied in one second, at a fraction of the cost.

SELECTED PEER-REVIEWED REFERENCES

Ting DS et al. Cannula-associated ocular injuries during cataract surgery: the North East England Study. Eye. 2016;30:764–5.

Rumelt S et al. The spectrum of iatrogenic intraocular injuries caused by inadvertent cannula release during anterior segment surgery. Arch Ophthalmol. 2007;125:889–92.

Ting DSJ et al. Cannula-associated ocular injuries during cataract surgery: a preventable intraoperative complication? Middle East Afr J Ophthalmol. 2017;24:54–6.

Kahawita S et al. Cyclodialysis cleft with late hypotony maculopathy after inadvertent cannula detachment. J Cataract Refract Surg. 2015;41:1107–8.

Prenner JL et al. Traumatic retinal break from viscoelastic cannula during cataract surgery. Arch Ophthalmol. 2003;121:128–9.

Dinakaran S, Kayarkar VV. Intraoperative ocular damage caused by a cannula. J Cataract Refract Surg. 1999;25:720–1.

Pandey P, Kirkby G. Cannula detachment during cataract surgery: results of a survey. Can J Ophthalmol. 2012;47(3):280–3.

INSTRUCTIONS FOR USE

Simple. Intuitive. One Second.

Cannusafe™ is applied by the scrub practitioner during syringe preparation. No training required. The surgeon is entirely uninvolved. The following illustrations demonstrate the application process.

STEP BY STEP

Pick up the Cannusafe from the sheet
One unit per syringe-cannula assembly. The sheet contains 10 units — sufficient for the procedure with spares for cannula changes.
Thread the cannula tip through the central aperture
The aperture is sized to accommodate all standard cannula sizes. The cannula passes through freely but the hub is arrested on any detachment.
Peel adhesive arms and press to syringe barrel
One arm each side. Press firmly for secure adhesion. The Cannusafe is now mechanically secured to the syringe.
Label the syringe using the integrated surface
Write the drug name on the labelling surface. Mandatory BS ISO 26825:2020 compliance is now complete. Hand to surgeon.

Designed to Secure.Engineered to Protect.

Two Mandatory Requirements. One Elegant Solution.